Best friends are the ones who support you for life, and are always there for you. Their mere presence calms you when you need a shoulder to lean on. However, sometimes, no matter the effort, friendships don’t work out. If that person or friendship is toxic and affects you negatively, then it’s wise to let go of that person. Astrology helps you identify people who might not be right for you, based on zodiac signs. Hence, we bring to you a list of zodiac signs who can never be friends.